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Two Baylor hospitals are the top U.S. centers for a clinical trial that potentially could yield a method to tame uncontrolled high blood pressure—without medication.

Medtronic is testing a minimally invasive procedure called renal denervation in what it calls the Symplicity trial.

One of the body’s primary methods for controlling blood pressure involves the sympathetic nervous system. The system includes the major organs that are responsible for regulating blood pressure: the brain, the heart, the kidney and the blood vessels themselves.